Acidic Fibroblast Growth Factor (aFGF) • Anti-Aging • Wound Healing

Acidic Fibroblast Growth Factor (aFGF)

Growth factors are vital proteins that circulate between cells and communicate signals necessary for the maintenance and regeneration of skin tissue cells. They are naturally secreted from cells and can provide skin with collagen and elastin formation, resulting in improved firmness and elasticity. Aging and environmental stress can damage skin, but growth factors can help to repair this.

Growth factors can be stabilized by properly formulating your product to a pH of 5-6 and with a glycerin content of 10-50% with a higher percentage being preferred. According to the the following linked study, a combination of phosphates or citric acid is the preferred pH buffer to inhibit reactions and stabilize growth factors at room temperature. (See study here:  Stabilizing Human Growth Factors)

INCI Nomenclature: sh-Polypeptide-11 (or) rh-Polypeptide-11, Aqua, Monosodium Phosphate, Disodium Phosphate, Radish Root Ferment Filtrate
Appearance: Clear to slightly hazy liquid
Molecular Weight: 16000 g/mol
Solubility: Water Soluble
pH: 5.8
Solution Concentration: 10 mcg/ml
Suggested Use Levels:  4-6% 
Suggested Applications: Skin care, anti-aging, wound care
Formulation Notes: Adust to an optimal pH of 5-6 the addition of glycerin between 10-50% is recommended to stabilize the Growth Factor at room temperature, otherwise refrigeration at 4C is recommended. (See linked PDF in description)
Storage: Protected from direct light and humidity at a temperature of 50°-77°F 
Shelf life: 24 months, properly stored, in a sealed container, refrigerated at 33°F-39°F
This product should be added to a formulation at the recommended usage rate.

All products sold are cosmetic grade; External Use Only; Cosmetic & Personal Care Formulations Only.